- This topic has 10 replies, 4 voices, and was last updated 9 years, 9 months ago by
.
-
Posts
-
When Ardea finally get their exclusive license to market Allopurinol, I'd like to bet $500 that the packaging is brown and cherry red.
?
Brown and CHerry red is very appropriate because those are the mose common colors seen during a vicious?anal rape.
If this “re-patent” of a drug that lost it;s patent decades ago?goes through, I will make it my life's work to bring down the FDA and see some of the crooked bastards behind bars, even if it means going into politics and losing my immortal soul (yeah right.)
Stealing money from the ill is about as low as mankind sinks.
How can it be stealing, he tried to ask innocently whilst secretly stirring vigorously? It is research:
“Allopurinol is an FDA approved treatment for high uric acid levels and gout. In this clinical research study, specialists are studying the appropriate doses of allopurinol. If you take part in this study, the study doctor will see you monthly over the next 6 months to optimize your treatment, with the goal of reducing your gout attacks. This will help researchers to see how people respond to different doses of the gout medication allopurinol.”
?
The colchicine trial that led to Colcrys:
“This study is a multicenter, randomized, double-blind, placebo-controlled, parallel group, dose-comparison to determine the efficacy and safety of a standard-dose of colchicine (4.8 mg) versus low-dose colchicine (1.8 mg) or placebo for acute gout flares.”
?
For the sake of completeness, I should point out that the first quote is from the marketing company for the allopurinol scam, whereas the second quote is from the medical trials official description in the colchicine scam.
It is close enough for me to worry.
The big difference between the rape of cochicine and the potential rape of allopurinol is that they invented the duplicitous term, orphan drug, for drugs like colchicine that existed LONG before anyone knew that North America existed (except those living there.) Thus colchicine never was patented. SO they invented a crooked way to patent it.
?
Allopurinol was, of course ZYLOPRIM, patented by Burroughs-Wellcome in 1966. Following U.S. patent law, that patent expired 17 (or 20) years later, or even later (not sure of the legalitie)?with court extensions. But it would take a sea change in patent law to repatent an expired patent because someone did some tests on it.
As far as I know, no drug that has gone off patent has ever gotten back ON.
But, given the colchicine debacle I am sure that peole in the U.S. FDA are being well bribed to do what they are told by the big VERY RICH drug companies, nothing would surprise me. Pulling the wool over the wooly-headed Congress and incompetent executive branch, who know how to do nothing but wage war, is small potatoes.
You are spot on re the patent issue, zip2play, and I have not worked out exactly what is going on. I just know that something is happening, so I started a little scaremongering [sorry]
?
It may end up being something helpful, like an allopurinol combo that has more benefits for gout sufferers. If that is so, then fair play, and good luck to them.
?
My problem is the “fair play” angle.
?
There is clearly something happening that is not being explained here. Every pharma company complains about the high cost of clinical trials, yet?Ardea are clearly investing massively in the current allopurinol trials. I know that marketing companies get really rich on the back of patented drugs, but this is the first time I have seen a marketing company being used to push clinical trials. They are spending massively on Facebook, and they are spending massively on general Internet advertising. No doubt I have only seen the tip of the iceberg, and there will be many more $millions on marketing in medical facilities and pharmacies. An in-depth study is beyond my means, but for on-line spend, they are certainly in the same league as Takeda who are promoting Uloric now it has patent protection.
?
A clear statement of intent from Ardea would be nice, but I will not hold my breath.
How about:
New ARDEA drug: 300 mg. allopurinol + 81 mg. aspirin…prolongs life better than allopurinol: $11 a pill.
They could call it: LIFFENOL or ETERNOL
So you guys are saying the FDA is going to let them do to Allopurinol what they did to Colchicine? Raising the price x 10. Limpy
limpy said:
So you guys are saying the FDA is going to let them do to Allopurinol what they did to Colchicine? Raising the price x 10. Limpy
Unless you fight it Limpy, they will do that (in my opinion). Give Ardea a ring, and see what they are up to.
zip2play said:
In all seriousness Limpy,
I don't think there is a legal basis for patenting allopurinol.
Yeah, but 3 years ago, did you expect to see colchicine protected as it is now?
I have not figured out how they will make profits, but no company spends this amount of money without good expectation of a return.
Keith Gout Advisor said:
zip2play said:
In all seriousness Limpy,
I don't think there is a legal basis for patenting allopurinol.
Yeah, but 3 years ago, did you expect to see colchicine protected as it is now?
I have not figured out how they will make profits, but no company spends this amount of money without good expectation of a return.
No, but again they used some sort of distorted logic about “orphaned drugs” that might pull the wool over some judges.
In the last 5 years, Pfizer, arguably the most powerful pharmaceutical powerhouse on the planet, tried EVERYTHING to keep the effective?patent on Lipitor, the biggest selling drug the world has ever seen. They got extensions in court for several years on bogus claims.?They even paid a generic maker BILLIONS to NOT sell the alternative.Now they are using a scheme involving a “Lipitor coupon” with false claims to continue selling the patented med instead of RANBAXY's newly awarded atorvastatin permission. (This generic exclusivity lasts for 6 months with Ranbaxy then anyone can enter the market.)
?
My point is that if even PFIZER with more lawyers than Carter has little liver pills cannot repatent Lipitor, it simply cannot be done.
?
So yeah, colchicine/Colcrys was an unimagined abomination but patenting allopurinol would be an order of magnitude more egregious.
?
There are also numbers to consider: far fewer people were regular users of colchicine but a LOT of people are on daily allopurinol.
- You must be logged in to reply to this topic.