Thank you both for you responses. I am now taking 300mg a day and have been for 4 days now. I am due for another uric acid test next week. I still have pain in my foot and can not walk normal. It has been with me now for about 6 weeks I think (not counting the prior 4 months with the big toe). Any ideas on how much longer before I can hope to walk without a limp. I am so used to being extremely phyiscally active and this sedentary life style is driving me insane.